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Library preparation for NGS

The right kit for your application

Our DNA library preparation technology is designed to streamline your NGS workflow, regardless of your application. Maximize the coverage and complexity of your libraries, so you can be confident in your results the first time and every time after. From the Lotus DNA Library Prep Kit’s flexible workflow to the xGen Prism DNA Library Prep’s superior performance with difficult samples, we have the right kit for your application.

  • Achieve high coverage and library complexity
  • Pair seamlessly with IDT’s comprehensive hybrid capture product line
  • Attain confidence in your results from the most challenging samples for projects large and small

Library prep is a necessary step to turn input DNA into final libraries before target capture or sequencing. Our library preparation solutions can help you no matter your application. Use the table below to choose the right kit for your samples.

KitLotus DNA Library Prep Kit xGen Prism DNA Library Prep Kit
Input range 1–250 ng 1–250 ng
Compatible sample types

High quality genomic DNA
DNA from formalin-fixed, paraffin-embedded (FFPE) samples

High quality genomic DNA
DNA from formalin-fixed, paraffin-embedded (FFPE) samples
Cell-free DNA (cfDNA)

Fragmentation Enzymatic Mechanical
Adapters/indexing primers

xGen Stubby Adapter and UDI Primers Pairs

xGen UDI-UMI AdaptersCustom NGS Adapters

Custom NGS Adapters

xGen UDI Primer Pairs and included adapters
Best applications Routine library prep Detection of low-frequency variants in difficult samples

Lotus DNA Library Prep Kit

Rapid, easy, and flexible enzymatic library preparation workflow that is compatible with our suite of custom adapters and xGen capture products.

xGen Prism DNA Library Prep Kit

The xGen Prism DNA Library Prep Kit empowers sensitive and accurate variant detection from degraded samples, such as cell-free DNA (cfDNA) or formalin-fixed, paraffin-embedded (FFPE) samples.