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Custom DNA & RNA Articles

Put an end to codon usage bias with these helpful tips

Most amino acids are determined by more than one codon and these synonymous codons are not equally used, creating codon usage bias. Specific sequences are favored over others when coding for certain amino acids in certain organisms, making it difficult to work with genes in the lab when expression must take place outside the native organism. This makes it important to avoid codon usage bias, as this article explains.