Archer next generation sequencing (NGS) technology offers flexible assay solutions compatible with a range of sample types (FFPE, frozen, cytology, FNA, blood), nucleic acid inputs (DNA, RNA, ctDNA), and variant classes (SNVs, indels, CNVs, MSI, TMB). It also enables easier adoption, training, and sustained use across multiple panels.
Archer NGS assay solutions are powered by AMP chemistry—engineered for accurate and comprehensive detection of clinically relevant genomic alterations.
AMP chemistry in Archer assay solutions uses Molecular Barcode Adapters (UMIs) for error correction, multiplexing, and sample tracking. A universal primer site enables novel fusion detection and sensitive amplification of degraded samples in solid tumor and blood cancer research.
AMP primers in Archer NGS assay solutions function independently, allowing easy customization of panel content without sacrificing performance. Primer and coverage uniformity, along with on-target rates, remain high—even as primer pool size scales across small to large panels.
AMP chemistry in Archer NGS assay solutions enhances sensitivity for low-allelic fraction variants, even with degraded DNA, RNA, or ctDNA. Its design supports FFPE and other low-quality inputs common in solid tumor research.
Archer NGS library preparation is simple, fast, and designed to minimize potential user errors for your lab.
Parallel workflows for Archer research assay solutions—VARIANTPlex™, FUSIONPlex™, LIQUIDPlex™, and IMMUNOVerse™: Library prep, sequencing, and analysis follow similar protocols, enabling lab efficiencies and streamlined NGS workflows.
Flexible formats:
Archer NGS library prep supports lyophilized reagents in breakaway 8-tube strips for small runs or 96-well plates for high-throughput workflows. Liquid reagents are also available in 24- and 96-reaction kits.
Efficient workflows:
Archer NGS enables parallel library prep and sample indexing, allowing all libraries to be sequenced together—streamlining operations and maximizing lab efficiency.
Archer Analysis is a powerful bioinformatics platform designed to streamline data interpretation across all Archer NGS assay solutions, available as a hosted or local solution.
Archer Analysis delivers confident, clear results with integrated QC metrics, error correction, and visualized outputs. Easily connect with LIMS or third-party annotations, and generate customizable reports to streamline your Archer NGS data interpretation.
Fusions drive up to 40% of soft tissue sarcomas. Learn how Archer NGS AMP™ technology overcomes FFPE challenges to improve fusion detection and CGP accuracy.
Keep NGS panels relevant—Archer NGS makes adding biomarkers easier.
Archer NGS overcomes key challenges in solid tumor oncology research.
Archer NGS tackles key challenges in blood cancer profiling workflows.
Archer NGS enables immune profiling and biomarker discovery in cancer.
Archer NGS helps overcome key challenges in genetic disease research.
Explore how Archer NGS can streamline your workflow with customizable assays and flexible formats. Request a consultation to tailor a solution for your lab’s unique needs.
Archer Analysis is available as an IDT-hosted SaaS product ("Archer Analysis Unlimited") or as locally-installed virtual machine. Archer Analysis Unlimited is designed to get labs up and running quickly, with no need to purchase server hardware or other IT resources. The Archer Analysis virtual machine is designed for labs with available IT resources and hardware in their institution. IDT Sales Managers can help you pick the right version of software for your lab.
Zheng Z, Liebers M, Zhelyazkova B, et al. Anchored multiplex PCR for targeted next-generation sequencing. Nat Med. 2014;20(12):1479-1484. doi:10.1038/nm.3729
