Blood Cancer Research Icon

Archer™ VARIANTPlex™ Myeloid panel v2

Discover insights into myeloid-origin cancers with a targeted DNA panel

Detect single nucleotide variants, insertions, deletions, copy number variations, and internal tandem duplications with targeted NGS of 92 genes relevant for acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), Chronic Myeloid Leukemia (CML), Myeloid Sarcomas (MS), and lymphoid malignancies research.

Detect confidently with Archer VARIANTPlex NGS Panels for DNA.

Talk to a technical sales expert

Learn how the VARIANTPlex Myeloid panel can identify key genomic alterations for your research.

Request a consultation

Product details

Panel specifications

Specifications
Targeted genes 92
Genomic alterations SNVs, Indels, CNVs, ITDs
Input nucleic acid required* ≥10 ng
Recommended number of reads 6 M
Hands-on time <3.5 hours
Total library prep time 1.5 days
Platform compatibility Illumina®
Reagent format Lyophilized or liquid
Supported sample types Blood, bone marrow, fresh frozen, BMMC, PBMC

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

Gene targets

ABL1
ANKRD26
ASXL1
ATRX
BCOR
BCORL1
BRAF
BRCC3
BTK
CALR
CBL
CBLB
CBLC
CCND2
CDC25C
CDKN2A
CEBPA
CREBBP
CSF3R
CTCF
CUX1
CXCR4
DCK
DDX41
DHX15
DNMT3A
EED
ETNK1
ETV6
EZH2
FBXW7
FLT3
GATA1
GATA2
GNAS
GNB1
HRAS
IDH1
IDH2
IKZF1
IL7R
JAK1
JAK2
JAK3
KDM6A
KIT
KMT2A
KMT2D
KRAS
LUC7L2
MAP2K1
MPL
MYC
MYD88
NF1
NOTCH1
NPM1
NRAS
NUDT15
PAX5
PDGFRA
PHF6
PPM1D
PRPF8
PTEN
PTPN11
RAD21
RBBP6
RPS14
RUNX1
SAMD9
SAMD9L
SETBP1
SETBP1
SF3B1
SH2B3
SLC29A1
SMC1A
SMC3
SRSF2
STAG2
STAT3
STAT5B
TET2
TP53
TPMT
U2AF1
U2AF2
UBA1
UBTF
WT1
XPO1
ZRSR2

Interested in adding a few genes to this panel?

Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

Customize today

Benefits

  • Detect confidently—A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Archer Analysis empowers you to detect confidently.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the VARIANTPlex Myeloid panel can identify key genomic alterations for your research.

Request a consultation

Frequently asked questions

Related products

References

RUO23-2346_001