Welcome to the IDT family!
Your product is now available from Integrated DNA Technologies.
Many of the Swift products you have grown to love are now part of our new complete portfolio, xGen™ NGS. Through this new partnership we are pleased to offer you comprehensive next generation sequencing solutions.
xGen NGS—made for you.
Unsure of what products are available? Or, perhaps you’d like guidance on which products are compatible? If so, try our xGen NGS Solutions Builder Tool today.
Welcome to the IDT family!
Find Archer now at IDT!
All Archer information is now available on IDT’s website. You can view Archer assays alongside IDT’s xGen™ NGS portfolio to find the best next generation sequencing solution for your lab.
Confidently detect more with Archer NGS assay solutions for your solid tumor, blood cancer, immune profiling, and genetic disease research.
- Products
- Next Generation Sequencing
- Library Preparation
- Adapters & Primers for NGS Sequencers
- xGen for Ultima Genomics Legacy
xGen™ for Ultima Genomics®—Legacy
Trusted IDT xGen NGS chemistries for emerging sequencers
These products are legacy versions of IDT’s xGen for Ultima Genomics®, and are intended for use by existing customers only.
xGen NGS—made platform-agnostic
- Workflow step
- Method
- Anchored Multiplex PCR
- Adapters & Primers for NGS Sequencers
- Tools
- NGS automation
Ordering
Find the latest version of these reagents here.
Product data
Methyl-seq library preparation workflow comparisons
The xGen Methyl-Seq DNA Library Prep Kit has a post-bisulfite library preparation workflow to maximize library complexity by converting bisulfite-induced single-stranded fragments directly into library molecules. Traditional methods construct libraries from dsDNA using methylated adapters followed by bisulfite conversion that leads to significant library loss due to bisulfite-induced DNA fragmentation. The random priming methods are also post-bisulfite but have reduced library complexity due to a lower efficiency biased workflow (see Table 2; Figure 3).
Resources
User guides and protocols
Index files
Safety data sheets
Certificates of analysis (COAs)
References
- Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet. 2012 May 29;13(7):484-92. doi: 10.1038/nrg3230. PMID: 22641018.
- Luo C, Keown CL, Kurihara L, et al. Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex. Science (New York, NY). 2017;357(6351):600-604.
- Luo C, Rivkin A, Zhou J, et al. Robust single-cell DNA methylome profiling with snmC-seq2. Nat Commun. 2018;9(1):3824.